You Have Been Asked to Design a Synthetic DNA Motif,able

You have been asked to design a synthetic DNA motif,able to bind transcriptional regulatory proteins.The location on this motif that you will design for protein binding is the

A) minor groove of the DNA double helix.
B) major groove of the DNA double helix.
C) phosphate backbone of the DNA double helix.
D) sugar backbone of the DNA double helix.
E) available hydrogen-bonds of bases in single-stranded DNA.