How can mutations in different genes,functioning in different cells,lead to the same disease? From the following,choose the best responses to complete the sentences: "Physiological function requires that multiple cells work together.Various defects in different cells can impair function,leading to ________ that are indistinguishable at the level of the whole organism.In Charcot-Marie-Tooth disease,motor nerve function can be impaired either by a problem within ________,or a problem in ________ causing ________."
A)defects; somatic cells; oligodendrocytes; demyelination
B)symptoms; motor neurons; Schwann cells; demyelination
C)symptoms; sensory neurons; Schwann cells; fast axonal transport
D)genotypes; dendrites; axons; fast axonal transport

Question

Quizplus · Accepted Answer

Charcot-Marie-Tooth disease is a neurological disorder that affects the peripheral nervous system. Motor nerve function can be impaired due to demyelination caused by a problem in either motor neurons or Schwann cells. As physiological function requires the coordination of multiple cells, defects in different cells can have a similar effect on the organism, leading to indistinguishable symptoms. Therefore, option B is the best choice as it correctly identifies the cells involved and the cause of the impairment in Charcot-Marie-Tooth disease.

How Can Mutations in Different Genes,functioning in Different Cells,lead to the Same