Which of the following is the most stable conformation of cis-1-ethyl-3-isopropylcyclohexane?
A)I
B)II
C)III
D)IV

Question

Which of the following is the most stable conformation of cis-1-ethyl-3-isopropylcyclohexane? 
A)I 
B)II 
C)III 
D)IV

Quizplus · Accepted Answer

The most stable conformation of cis-1-ethyl-3-isopropylcyclohexane is C (III) because both the ethyl group and isopropyl group prefer equatorial positions to minimize steric hindrance. The axial position would cause more steric hindrance due to the eclipsed conformations with the cyclohexane ring. Therefore, the equatorial positioning of the substituents is preferred for stability. In this conformation, both the ethyl group and the isopropyl group are present in equatorial positions, minimizing steric hindrance and leading to greater stability.

Which of the Following Is the Most Stable Conformation of Cis-1-Ethyl-3-Isopropylcyclohexane