What is a major problem with Friedel-Crafts alkylation?
A)It requires high temperatures.
B)The conditions are too acidic.
C)The starting material is frequently over-alkylated.
D)The products coordinate with the aluminum chloride.

Question

Quizplus · Accepted Answer

The major problem with Friedel-Crafts alkylation is that the starting material is frequently over-alkylated, meaning that more alkyl groups are added to the starting material than desired. This not only reduces the yield of the desired product, but can also lead to the formation of unwanted byproducts.

What Is a Major Problem with Friedel-Crafts Alkylation