Why can't you use acidic conditions (such as aqueous hydrochloric acid)for the addition of a Grignard reagent to a ketone?
A)Because the Grignard reagent will react with the acid and be quenched
B)Because the ketone will be protonated and thus unreactive
C)Because the ketone will form an unreactive enol
D)Because the Grignard reagent won't dissolve in aqueous solutions

Question

Quizplus · Accepted Answer

Grignard reagents are highly reactive towards acids. If an acidic condition is present, the Grignard reagent will react with the acid, leading to its deactivation before it can react with the ketone. This is because the Grignard reagent, being a strong base, will be protonated by the acid, effectively destroying its reactivity towards the ketone.

Why Can't You Use Acidic Conditions (Such as Aqueous Hydrochloric