In the preparation of primary amines,how can direct nucleophilic substitution between NH₃ and alkyl halide be made more practical than reacting NH₃ and the alkyl halide in a 1:1 ratio? A)Use a large excess of NH₃. B)Use a large excess of alkyl halide. C)Use a limited amount of NH₃. D)Make the alkyl halide sterically hindered.

Question

Quizplus · Accepted Answer

Using a large excess of NH3 (ammonia) helps drive the reaction towards the formation of the primary amine by shifting the equilibrium, making the process more practical than a 1:1 ratio, which could lead to secondary or tertiary amines.

In the Preparation of Primary Amines,how Can Direct Nucleophilic Substitution