Which of the following correctly describes the Merrifield synthesis?
A)It uses a solid phase technique for the synthesis of peptides.
B)It uses DCC (dicyclohexylcarbodiimide)to form the amide bond in a peptide synthesis.
C)It uses BOC (tert-butoxycarbonyl)as a protecting group for peptide synthesis.
D)It uses aqueous phase techniques for the synthesis of large polypeptides.

Question

Quizplus · Accepted Answer

The Merrifield synthesis is known for its solid-phase peptide synthesis technique, where the growing peptide chain is attached to a solid resin support. This allows for easier purification and isolation of the peptide product.

Which of the Following Correctly Describes the Merrifield Synthesis