What are the basic steps in the Merrifield peptide synthesis?
A)Coupling and hydrolysis
B)Hydrolysis and deprotection
C)Deprotection and hydrogenation
D)Coupling and deprotection

Question

Quizplus · Accepted Answer

The Merrifield peptide synthesis involves two basic steps: coupling, where the amino acid monomer is added to the growing peptide chain, and deprotection, where the protecting group on the side chain of the amino acid is removed to allow for the next coupling step. Therefore, the best choice is D, coupling and deprotection.

What Are the Basic Steps in the Merrifield Peptide Synthesis