A patient's laboratory coagulation test results in an immediate correction of the PT and aPTT after mixing studies and no correction after performing the PT and aPTT after a 2-hour incubation at 37°C. What is the possible deficiency or inhibitor?
A) Factor deficiency
B) Lupuslike anticoagulant
C) F-VIII inhibitor
D) F-V loss

Question

Quizplus · Accepted Answer

The immediate correction suggests a factor deficiency, but the lack of correction after incubation indicates a time-dependent inhibitor, such as a factor VIII inhibitor.

A Patient's Laboratory Coagulation Test Results in an Immediate Correction