The inability of the cell membrane to control the movement of the chloride ion into and out of the cell is the cause of both cystic fibrosis and cholera.

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In cystic fibrosis, a mutation in the CFTR gene results in the malfunction of the protein responsible for chloride ion transportation across the cell membrane. In cholera, the toxin produced by Vibrio cholerae affects the chloride ion channels in the intestinal cells, leading to excessive chloride ion secretion and dehydration. In both cases, the inability to control the movement of chloride ions is a crucial factor in the development of the disease.

The Inability of the Cell Membrane to Control the Movement