Describe the molecular and transmission characteristics of Leber's hereditary optic neuropathy LHON .
A)maternal inheritance,which includes mtDNA lesions
B)cytoplasmic inheritance,which includes cpDNA lesions
C)X- linked recessive
D)cytoplasmic inheritance,which includes mtDNA lesions
E)dominant maternal inheritance

Question

Quizplus · Accepted Answer

LHON is characterized by cytoplasmic inheritance, specifically caused by lesions in mitochondrial DNA. It is inherited from the mother due to the fact that only the egg contributes mitochondria to the developing embryo. The transmission of LHON does not follow the normal pattern of Mendelian inheritance.

Describe the Molecular and Transmission Characteristics of Leber's Hereditary Optic