Which of the following is not correct concerning 2,3-bisphosphoglycerate (BPG)?
A)It binds at a distance from the heme groups of hemoglobin.
B)It binds with lower affinity to fetal hemoglobin than to adult hemoglobin.
C)It increases the affinity of hemoglobin for oxygen.
D)It is an allosteric modulator.
E)It is normally found associated with the hemoglobin extracted from red blood cells.

Question

Quizplus · Accepted Answer

2,3-bisphosphoglycerate (BPG) actually decreases the affinity of hemoglobin for oxygen, allowing for easier release of oxygen in tissues with lower oxygen concentrations. Thus, choice C is not correct. The other choices are all correct: A) BPG binds at a distance from the heme groups of hemoglobin, B) BPG binds with lower affinity to fetal hemoglobin than to adult hemoglobin, D) BPG is an allosteric modulator, and E) BPG is normally found associated with the hemoglobin extracted from red blood cells.

Which of the Following Is Not Correct Concerning 2,3-Bisphosphoglycerate (BPG)