What General Statement Is Most Accurate Concerning Hormone Replacement Therapy

What general statement is most accurate concerning hormone replacement therapy (HRT) ?

A) Most women should take HRT for one to two years following menopause.
B) Women should begin HRT when she starts experiencing perimenopausal symptoms.
C) Recent research has found that much of the concern about the safety of HRT is unfounded.
D) As a general practice,women should not take HRT.
E) There are pros and cons of HRT that need to be evaluated on a case-by-case basis.