An experiment is carried out to characterize newly discovered immunoglobulins. Specificity of the immunoglobulin could be determined by studying the:
A) C region of the light chain.
B) C region of the H chain.
C) Complementary-determining region.
D) Framework regions.

Question

Quizplus · Accepted Answer

The specificity of an immunoglobulin is determined by the complementary-determining region (CDR) of the variable domains in the H and L chains. The C region of the H and L chains are important for determining the functional properties of the antibody, but not for specificity. The framework regions are also important for the three-dimensional structure of the antibody, but do not directly contribute to specificity.

An Experiment Is Carried Out to Characterize Newly Discovered Immunoglobulins