The sequence for the processing of proteins produced within the cell is...
A) Proteins are broken into fragments, transported to the rough endoplasmic reticulum, fuse with a Golgi vesicle containing class II MHCs, and this complex is transported to the plasma membrane.
B) Proteins are broken into fragments within a vesicle, which fuses with a Golgi vesicle containing class I MHCs, and this complex is transported to the plasma membrane.
C) Proteins are broken into fragments within a vesicle, which fuses with a Golgi vesicle containing class II MHCs, and this complex is transported to the plasma membrane.
D) Proteins are broken into fragments, transported to the rough endoplasmic reticulum, combined with class II MHCs, move to the Golgi apparatus, then to the plasma membrane.
E) Proteins are broken into fragments, transported to the rough endoplasmic reticulum, combined with class I MHCs, move to the Golgi apparatus, then to the plasma membrane.

Question

Quizplus · Accepted Answer

Proteins are processed within the cell as follows: they are broken into fragments within the rough endoplasmic reticulum, combined with class I MHCs, transported to the Golgi apparatus for further processing, and ultimately transported to the plasma membrane where they are displayed for antigen recognition by immune cells. Therefore, choice E is the correct sequence for protein processing.

The Sequence for the Processing of Proteins Produced Within the Cell