Arrange the following events in endochondral ossification in proper sequence: (1) Cartilage matrix is calcified and chondrocytes die.
(2) Chondrocytes hypertrophy.
(3) Cartilage model is formed.
(4) Osteoblasts deposit bone on the surface of the calcified cartilage called the primary ossification center.
(5) Blood vessels from the periosteum invade calcified cartilage bringing in osteoblasts and osteoclasts.
A) 3, 2, 1, 5, 4
B) 3, 2, 5, 4, 1
C) 3, 2, 5, 1, 4
D) 3, 5, 2, 4, 1
E) 1, 3, 4, 5, 2

Question

Quizplus · Accepted Answer

The correct sequence of events in endochondral ossification is: cartilage model formation, chondrocyte hypertrophy, cartilage matrix calcification and chondrocyte death, invasion by blood vessels bringing osteoblasts and osteoclasts, and finally, osteoblasts depositing bone to form the primary ossification center.

Arrange the Following Events in Endochondral Ossification in Proper Sequence