What local effect would an RNA synthesis inhibitor have on DNA replication?
A) Primase would not be able to add bases to the DNA.
B) Primase would not be able to use DNA as a template.
C) Primase would be blocked from joining the holoenzyme complex.
D) Primase would not be able to provide primers for DNA polymerases.
E) There would be no effect on DNA replication.

Question

Quizplus · Accepted Answer

RNA synthesis is necessary for the synthesis of primers, which are required for DNA polymerase to begin replicating the DNA strand. If RNA synthesis is inhibited, primase would not be able to produce primers, thereby halting DNA replication. Choices A, B, and C are all related to the function of primase, but choice D directly addresses the impact on DNA replication. Choice E is incorrect because inhibition of RNA synthesis would have a direct effect on DNA replication.

What Local Effect Would an RNA Synthesis Inhibitor Have on DNA