Suppose that a certain mRNA is transcribed at a normal rate in the nucleus,but it is found at very low levels in the cytoplasm.Which of the following would be the most plausible explanation for this phenomenon?
A) A defect in the addition of the poly A tail on the pre-mRNA
B) A defect in a spliceosome
C) A defect in nucleic acid hybridization
D) Overactive termination
E) A defect in the promoter

Question

Quizplus · Accepted Answer

The addition of the poly A tail to pre-mRNA is necessary for transport of the mRNA from the nucleus to the cytoplasm. Without it, the mRNA cannot be exported to the cytoplasm for translation, resulting in low levels of the mRNA in the cytoplasm.

Suppose That a Certain MRNA Is Transcribed at a Normal