Intracranial Volume = Brain Volume + CSF Volume + Blood Volume is the basis behind which of the following?
A) Cerebral perfusion pressure
B) Monroe-Kellie doctrine
C) Mean arterial pressure
D) Traumatic brain injury

Question

Quizplus · Accepted Answer

The equation Intracranial Volume = Brain Volume + CSF Volume + Blood Volume is the basis behind the Monroe-Kellie doctrine, which suggests that since the skull is a closed, rigid container, any increase in volume of one component (brain, CSF, or blood) must be compensated by a decrease in volume of another component to maintain stable intracranial pressure. Traumatic brain injury can be a result of failure to compensate for an increase in intracranial volume, but it is not the basis behind the equation. Cerebral perfusion pressure and mean arterial pressure are not directly related to this equation.