Which of the following statements applies to the E2 mechanism?
A) It occurs with inversion of stereochemistry.
B) It occurs with racemization of stereochemistry.
C) It proceeds through the more stable carbocation intermediate.
D) The C-H and C-X bonds that break must be anti.
E) Use of a bulky base gives the more highly substituted alkene product.

Question

Quizplus · Accepted Answer

In an E2 mechanism, the C-H and C-X bonds must be anti-periplanar to each other for the elimination to occur. This allows for the proper orbital alignment necessary for the concerted elimination process.

Which of the Following Statements Applies to the E2 Mechanism