Restriction endonucleases are powerful enzymes used in molecular biological experimentation. Which of the follwing chemical bonds do these enzymes target?
A) disulfide
B) N-glycosidic
C) O-glycosidic
D) peptide
E) phosphodiester

Question

Quizplus · Accepted Answer

Restriction endonucleases target phosphodiester bonds in the DNA backbone, cutting the DNA at specific sequences.  Restriction endonucleases are enzymes that cut DNA at or near specific recognition nucleotide sequences. The "cutting" involves the hydrolysis of the phosphodiester bond in the DNA strands.

Restriction Endonucleases Are Powerful Enzymes Used in Molecular Biological Experimentation