In a case of immediate hypersensitivity the immune system responds with an allergic response on the first exposure to the allergen.

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In a case of immediate hypersensitivity, also known as type I hypersensitivity, an individual must have been previously exposed to the allergen for the immune system to mount an allergic response. The first exposure typically results in sensitization rather than an allergic reaction. It is only upon subsequent exposure to the same allergen that the immune system responds with an immediate allergic reaction.

In a Case of Immediate Hypersensitivity the Immune System Responds