If the DNA strand shown below is used as a template for RNA polymerase, what would be the sequence of the resultant mRNA following transcription?
5′-CATTCCATAGCATGT-3′
A) 5′-ACAUGCUAUGGAAUG-3′
B) 5′-CAUUCCAUAGCAUGU-3′
C) 5′-GUAAGGUAUCGUACA-3′
D) 5′-UGUACGAUACCUUAC-3′

Question

Quizplus · Accepted Answer

The mRNA sequence is complementary to the DNA template strand and is synthesized in the 5' to 3' direction. The DNA template 3'-5' strand is 3'-GTACGATATGGAATG-5', so the mRNA is 5'-ACAUGCUAUGGAAUG-3'. DNA template strands are used by RNA polymerases to direct the synthesis of an RNA. The nucleotides incorporated are ribonucleotides and they will be complimentary to the sequences of the template strand and oriented in the antiparallel direction. Whenever RNA polymerase encounters an adenosine, it will incorporate a uracil into the RNA molecule.

If the DNA Strand Shown Below Is Used as a Template