You are studying the effects of a compound on the respiratory activity of isolated mitochondria. Your experiments demonstrate that oxygen consumption is normal when pyruvate and malate are used as well as when succinate is added. However, you find that the production of ATP is severely impaired with addition of the compound. These results most closely resemble the effects that would be seen by the addition of the following electron transport inhibitor to your system?
A) antimycin A
B) azide
C) dinitrophenol (DNP)
D) oligomycin
E) rotenone
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