When a mixture of glucose 6-phosphate and fructose 6-phosphate is incubated with the enzyme phosphohexose isomerase (which catalyzes the interconversion of these 2 sugars) until equilibrium is reached, the final mixture contains twice as much glucose 6-phosphate as fructose 6-phosphate. Which one of the following statements is best applied to this reaction outlined below? (R = 8.315 J/mol·K; T = 298 K) Glucose 6-phosphate → fructose 6-phosphate A) ΔG^0' is incalculably large and negative B) ΔG^0' is -1.72 kJ/mol C) ΔG^0' is zero D) ΔG^0' is +1.72 kJ/mol E) ΔG^0' is incalculably large and positive

Question

Quizplus · Accepted Answer

The equilibrium constant (K) for the reaction is 0.5 (since there is twice as much glucose 6-phosphate as fructose 6-phosphate). Using the equation ΔG^0' = -RT ln K, we find ΔG^0' is +1.72 kJ/mol.

When a Mixture of Glucose 6-Phosphate and Fructose 6-Phosphate Is