When a mixture of 3-phosphoglycerate and 2-phosphoglycerate is incubated at 25°C with phosphoglycerate mutase until equilibrium is reached, the final mixture contains 6 times as much 2-phosphoglycerate as 3-phosphoglycerate. Which one of the following statements is most nearly correct, when applied to the reaction as written? (R = 8.315 J/mol·K; T = 298 K) 3-Phosphoglycerate → 2-phosphoglycerate A) ΔG^0' is −4.44 kJ/mol B) ΔG^0' is zero C) ΔG^0' is +12.7 kJ/mol D) ΔG^0' is incalculably large and positive E) ΔG^0' cannot be calculated from the information given

Question

Quizplus · Accepted Answer

The equilibrium constant (K) is 6, as there is 6 times more 2-phosphoglycerate than 3-phosphoglycerate. Using the equation ΔG°' = -RT ln(K), where R is 8.315 J/mol·K and T is 298 K, ΔG°' is calculated to be approximately -4.44 kJ/mol.

When a Mixture of 3-Phosphoglycerate and 2-Phosphoglycerate Is Incubated at 25°C