Indicate true (T) and false (F) statements below regarding differentiation of blood cells. Your answer would be a four-letter string composed of letters T and F only, e.g. TTTT.
( ) Most blood cells are derived from the pluripotent stem cells by a few cell divisions.
( ) Commitment to a specific differentiation path is a stepwise process.
( ) Upon contacting connective-tissue cells of the bone marrow, hematopoietic stem cells lose their stem-cell character and differentiate.
( ) Committed hematopoietic progenitor cells typically divide rapidly.

Question

Indicate true (T) and false (F) statements below regarding differentiation of blood cells. Your answer would be a four-letter string composed of letters T and F only, e.g. TTTT.
( )	Most blood cells are derived from the pluripotent stem cells by a few cell divisions.
( )	Commitment to a specific differentiation path is a stepwise process.
( )	Upon contacting connective-tissue cells of the bone marrow, hematopoietic stem cells lose their stem-cell character and differentiate.
( )	Committed hematopoietic progenitor cells typically divide rapidly.

Quizplus · Accepted Answer

Hematopoietic stem cells interact with the stromal cells in the bone marrow to maintain their stemness, while the committed progeny go on to divide many times rapidly to create specialized blood cells. Commitment of progenitor cells to the production of each of the various blood cells occurs in a stepwise manner.

Indicate True (T) and False (F) Statements Below Regarding Differentiation