Which method of fragmenting DNA would not be useful for sequencing a genome for the first time?
A)Complete digestion with a restriction enzyme
B)Partial digestion with a restriction enzyme
C)Forcing DNA through a thin needle
D)Exposing DNA to ultrasound energy

Question

Quizplus · Accepted Answer

Complete digestion with a restriction enzyme would cut the DNA into too many small fragments, making it difficult to assemble the genome sequence for the first time.

Which Method of Fragmenting DNA Would Not Be Useful for Sequencing