Organification defect specifically concerns the inability of the thyroid to covalently bind iodide to tyrosine residues in the colloid.This reaction is performed by:
A)Thyroid peroxidase.
B)The sodium-iodide transporter.
C)The TSH receptor.
D)Iodotyrosine deiodinases.
E)Thyroglobulin.

Question

Quizplus · Accepted Answer

The process of iodide binding to tyrosine residues in the colloid is performed by thyroid peroxidase. The sodium-iodide transporter and the TSH receptor are involved in the uptake and regulation of iodide by the thyroid gland. Iodotyrosine deiodinases are involved in the breakdown of iodotyrosine molecules. Thyroglobulin is a protein that serves as the precursor to thyroid hormones but is not directly involved in the iodide-tyrosine binding process.

Organification Defect Specifically Concerns the Inability of the Thyroid to Covalently