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Essential Genetics 6th Edition by Daniel Hartl
Edition 6ISBN: 978-1449686482Essential Genetics 6th Edition by Daniel Hartl
Edition 6ISBN: 978-1449686482 Exercise 12
Human papilloma virus (HPV) is present in greater than 90 percent of cervical cancers. HPV encodes two proteins, E6 and E7, that are potent contributors to its tumorigenicity. E7 is known to disable RB; E6 binds to p53 and targets it for degradation. Discuss how these activities might contribute to the development of the cancerous state in infected cells.
Explanation
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The retinoblastoma allele, or RB is cate...
Essential Genetics 6th Edition by Daniel Hartl
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