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Biochemistry 6th Edition by Reginald Garrett,Charles Grisham
Edition 6ISBN: 978-1305577206Biochemistry 6th Edition by Reginald Garrett,Charles Grisham
Edition 6ISBN: 978-1305577206 Exercise 16
A deficiency in 3-phosphoglycerate dehydrogenase can affect amino acid metabolism
Although serine is a nonessential amino acid, serine deficiency syndrome has been observed in humans. One such form of the syndrome is traceable to a deficiency in 3-phosphoglycerate dehydrogenase (see Figure 25.31). Individuals with this syndrome not only are serine-deficient, but also are impaired in their ability to synthesize another common amino acid, as well as a class of lipids. Describe why.
Although serine is a nonessential amino acid, serine deficiency syndrome has been observed in humans. One such form of the syndrome is traceable to a deficiency in 3-phosphoglycerate dehydrogenase (see Figure 25.31). Individuals with this syndrome not only are serine-deficient, but also are impaired in their ability to synthesize another common amino acid, as well as a class of lipids. Describe why.
Explanation
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Glycine is one of the amino acids that a...
Biochemistry 6th Edition by Reginald Garrett,Charles Grisham
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