Molecular Biology 5th Edition by Robert Weaver

Exercise 4

Type A histone acetyltransferases (HAT A's) contain a bromodomain and HAT B's do not. What do you predict would occur if HAT A's were missing this bromodomain What if HAT B's possessed this bromodomain If the bromodomains were reversed so that all HAT B's gained bromodomains and all HAT A's lost them, would HAT A's take over the role of HAT B's and vice versa Why or why not How would you answer this question experimentally