Urinalysis and Body Fluids 6th Edition by Majorie DiLorenzo, Susan Strasinger

Exercise 36

All states require newborn screening for PKU for early:

A. Modifications of diet

B. Administration of antibiotics

C. Detection of diabetes

D. Initiation of gene therapy

Step 1 of 2

Newborn screening test:

Newborns are monitored for inborn error of metabolism (IEM).

• Screening of newborns has elevated for including sensitive methods of detection and elevating levels of state-mandated test for inborn errors of metabolism.

• Currently many states require 30 and above metabolic disorder testing.

• These disorders make building up of unmetabolized toxic food substances.

PKU (phenylketonuria):

• It is an inherited amino acid disorder caused by failure of inheriting gene which produce phenylalanine hydroxylase enzyme.

• Screening test for this disorder is available for early detection of abnormality.

• All states hold laws that require newborn screening for PKU.

• Earlier detection helps in modification of infant’s diet by avoiding milk that can eliminate formation of serum phenylalanine thereby preventing child’s mental abnormality.

Therefore, all states require screening for PKU in newborn for early “modification of diet”. Hence, the correct answer is option.