Urinalysis and Body Fluids 6th Edition by Majorie DiLorenzo, Susan Strasinger

Exercise 30

A disorder associated with polyuria and low specific gravity is:

A. Renal glucosuria

B. Minimal change disease

C. Nephrogenic diabetes insipidus

D. Focal segmental glomerulosclerosis

Step 1 of 2

Nephrogenic diabetes insipidus:

• Antidiuretic hormone (ADH) produced from hypothalamus of brain regulates the urine concentration.

• When the action of ADH is disturbed by inability of renal tubules to react ADH and failure of ADH secretion in hypothalamus, urine is excreted in increased level.

• Inability of renal tubules is called as nephrogenic diabetic insipidus.

• Nephrogenic diabetic insipidus can be inherited from medications or sex-linked recessive gene.

• Nephrogenic diabetes insipidus shows polyuria and low specific gravity in urine.

Therefore, “Nephrogenic diabetes insipidus” is associated with low specific gravity and polyuria. Hence, the correct answer is option .