Urinalysis and Body Fluids 6th Edition by Majorie DiLorenzo, Susan Strasinger

Exercise 65

Nonpathogenic granular casts contain:

A. Cellular lysosomes

B. Degenerated cells

C. Protein aggregates

D. Gram-positive cocci

Step 1 of 2

Granular casts:

• Rough and fine granular casts is seen in urinary sediment.

• It may have non-pathologic or pathologic significance.

• During metabolism, lysosomes of renal tubular epithelial cells forms granular casts, it is a non-pathologic condition.

• In diseased state granules shows disintegration of tubule cells, casts cells and protein aggregation.

• Increased metabolism during strenuous exercise causes increase of granular casts and also hyaline casts.

Therefore, non-pathologic granular casts have “cellular lysosomes”. Hence, the correct answer is option .