Quinolones Are a Group of Broad-Spectrum Antibiotics That Specifically Target
Quinolones are a group of broad-spectrum antibiotics that specifically target topoisomerase. Explain how this contributes to cell death in bacteria. Would you expect these drugs to kill hyperthermophilic prokaryotes too? Why or why not?
Eukaryotic chromosomes are a combination of proteins and DNA, which allows the cell to perform which four essential functions?
Bacterial DNA is primarily compacted by supercoiling and folding. Briefly describe each mechanism.
Histone proteins are the principal agents in chromatin packaging. The nucleosome core particle is a heterooctameric protein complex that contains two molecules each of the four histones H2A, H2B, H3, and H4. Describe the process of managing existing nucleosome core particles during replication and the process of adding these and new nucleosome core particles to DNA after the replication