In Mapping the Hd Gene Associated with Huntington Disease, Eventually
In mapping the HD gene associated with Huntington disease, eventually researchers narrowed down their hunt to four candidate genes within the mapped region. How did they identify one of these as the definitive HD gene?
In an organism, X, it is found to be impossible to generate loss-of-function mutants for most genes. There is an alternative method of introducing random mutations that can later be screened for the gene(s)in question. This can be accomplished by using insertions due to what structures?
Knockout libraries are available already prepared for some organisms such as Drosophila. These libraries are originally made by what method?
In nature, RNAi protects cells against infection by what kind of pathogen?