A Mutation That Changes a Gc Base Pair to at Is
A mutation that changes a GC base pair to AT is a(n): A)transition. B)transversion. C)induced mutation. D)missense mutation. E)synonymous mutation.
Huntington disease can strike at an earlier age and bring about a more rapid degeneration and death in successive generations within a family.This phenomenon can be explained by which mechanism? A)Presence of a transposable element in the gene B)Chronic exposure to mutagens in the environment C)Expansion of a trinucleotide repeat in the coding sequence of the gene D)Presence of an extra chromosome in the germ line E)Absence of a gene product that is involved in DNA repair
What is the consequence of a transversion mutation in duplex DNA? A)A purine is replaced by a pyrimidine, and a pyrimidine is replaced by a purine. B)A base pair is lost within the DNA of a gene, which causes a reading frameshift. C)A purine is replaced by another purine, and a pyrimidine is replaced by another pyrimidine. D)A base pair is added to the DNA within a gene, which causes a reading frameshift. E)The sequence of the DNA remains the same since the change involves proteins.
Achondroplasia is a form of dwarfism that is inherited in humans as an autosomal dominant.A survey in a small country showed that, within a 2-year period, there were 12 children with normal parents born with this disorder out of a total of 420, 000 births.What is the mutation rate in mutations/locus/generation? A)1)4 × 10-5 B)2)8 × 10-6 C)2)5 × 10-5 D)2)8 × 10-5 E)7)4 × 10-6