A Deficiency of ___________________ Results in Gray Platelet Syndrome:
A deficiency of ___________________ results in gray platelet syndrome:
D) High-molecular-weight vWF
E) Cyclo-oxygenase deficiency
Heparin induced thrombocytopenia is caused by:
A) Destruction of marrow megakaryocyte by heparin
B) Splenic sequestration of heparin antibody complex coated platelets
C) Heparin-antibody complex mediated platelet activation causing platelet consumption
D) Inhibition of platelet release reactions by heparin
E) Suppression of marrow megakaryocyte platelet production by heparin
The most important therapeutic intervention for suspected heparin-induced thrombocytopenia is:
B) Lepthirudin (recombinant form of hirudin)
E) Discontinuation of heparin
All of the following are characteristic of hereditary hemorrhagic telangiectasia (Rendu-Osler-Weber syndrome) except:
A) Telangiectatic lesions occur on mucus membranes.
B) Iron deficiency anemia is usually present.
C) Abnormal platelet aggregation in response to thrombin is present.
D) Epistaxis is common.
E) An autosomal inheritance pattern is present.