Pharmacology Study Set 4
Quiz 3 :
Time taken for the drug concentration to remain in the body is called duration of action. This determines the rapidness of the drug with respect of metabolism and excretion. The most common description is the plasma half-life (t½). Plasma half is defined as the time required by the plasma concentration of the drug to reduce to half after the administration. This varies from drug to drug. Some have in minutes and some have in days or hours.
Drug is the thing that acts on the certain organs and lowers the pain or the disease. Pharmacology as the name indicates it is the study of the medicines or the drug. It includes the administration of the drug, its action on a certain organ, their response and the amount of the drug to be administered for better results. Drug can be taken in the form of tablet or syrup called the oral administration or through subcutaneous, intravenous or in the form of gel. Exclusitivity is important for the pharmacy companies to prove their safety and efficiency and also to protect their data from the generic brands.
Drug metabolism is a process of changing the drug molecule chemically. The main site for metabolism is the liver. First the drug that is taken is absorbed in the intestinal mucosa then passes through the liver that is metabolized to less active form. From the liver the less active form is distributed all over the body. The adsorbed drugs remain in the body till they are converted into inactive form or got excreted. The primary site for excretion is the kidneys. The factors that influence the drug metabolism is • Age • Alcohol or smoking abuse • Liver or kidney failures that are the main sites for metabolism and excretion.