Quiz 30: Antiallergic and Antihistaminic Drugs

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Red blood cell consists of haemoglobin protein which is responsible for red colour of the blood and transport of oxygen to all the tissues of the body. Changes in the haemoglobin reduces the oxygen carrying capacity. Due to this deficiency the body experience certain symptoms like weakness, fatigue, irritability etc. These symptoms are caused due to the anemia. There are two types of anemia as an inherited anemia and deficiency anemia. Anemia is caused due to the reduction in an oxygen-carrying capacity of red-blood cells. An inherited anemia is caused due to the abnormal haemoglobin which is inherited genetically. Deficiency anemia is caused due to the reduction in haemoglobin amount because of haemorrhage, haemolysis or reduced RBCs production. This all conditions leads to reduction in amount of circulating haemoglobin in the blood. When the bone marrow is poisoned due to chemicals or anticancer drugs then it may also lead to impaired blood cell production. The most common reason behind the anemia is the lack of iron, cyanocobalamin or folic acid. This may produce morphological changes in the RBCs and WBCs. Most common cause of anemia is consumption of diet which lack appropriate amount of vitamins and minerals. After identification of the missing mineral or vitamin, a replacement therapy along with the diet changes can resolve the deficiency problem. There are different causes that may lead to any of the deficiency described above such as excessive blood loss, decreased RBC production due to anemia, bone marrow failure, increased RBC destruction and altered RBC production.

Red blood cell consists of haemoglobin protein which is responsible for red colour of the blood and transport of oxygen to all the tissues of the body. Changes in the haemoglobin reduces the oxygen carrying capacity. Due to this deficiency the body experiences certain symptoms like weakness, fatigue, irritability etc. These symptoms are caused due to anemia. There are two types of anemia as an inherited anemia and deficiency anemia. Anemia is caused due to the deficiency of iron, cyanocobalamin and folic acid. Deficiency type of anemia can be treated and is responsive to the replacement therapy. Anemia is caused due to the reduction in an oxygen-carrying capacity of red-blood cells. An inherited anemia is caused due to abnormal haemoglobin which is inherited genetically. Deficiency anemia is caused due to the reduction in the haemoglobin amount because of haemorrhage, haemolysis or reduced RBCs production. This all conditions leads to reduction in amount of circulating haemoglobin in the blood. The most common reason behind the anemia is the lack of iron, cyanocobalamin or folic acid. In iron deficiency anemia treatment, oral supplements of iron are mostly used. These medicines are used to increase the haemoglobin amount. For optimize absorption of oral supplements they should be taken at empty stomach. The common adverse effect associated with these oral tablets is gastric irritation, nausea and constipation. Hematinics are the medications that contain iron used to increase the haemoglobin level in blood. Drug interaction is observed when hematinics are taken along with the tetracycline and antacids. Tetracycline reduce the absorption of iron by chelating the iron. This also decrease the absorption of tetracycline. It is recommended to take the tetracycline and iron supplements with the gap of 2 hours.

Red blood cell consists of haemoglobin protein which is responsible for red colour of the blood and transport of oxygen to all the tissues of the body. Changes in the haemoglobin reduces the oxygen carrying capacity. Due to this deficiency the body experiences certain symptoms like weakness, fatigue, irritability etc. These symptoms are caused due to anemia. There are two types of anemia as an inherited anemia and deficiency anemia. Anemia is caused due to the deficiency of iron, cyanocobalamin and folic acid. Deficiency type of anemia can be treated and is responsive to the replacement therapy. Deficiency anemia is caused due to the reduction in haemoglobin amount because of haemorrhage, haemolysis or reduced RBCs production. This all conditions leads to the reduction in amount of circulating haemoglobin in the blood. The most common reason behind the anemia is the lack of iron, cyanocobalamin or folic acid. Nutritional deficiency along with haemorrhage, altered RBCs function and synthesis along with RBCs destruction are the main causes of iron deficiency. It can be treated with various iron supplements available in tablet, capsule or liquid form. To treat the deficiency caused by vitamin or mineral it is important to explain the patient the appropriate way and time to use the iron or any other supplements. The patient compliance plays here an important role. Hematocytic report may indicate the type of deficiency the patient is suffering from. It is important to consider patient condition, ongoing drugs and any physical condition that may affect the replacement therapy of vitamin or iron. Some patients are unable to take the oral supplements then parenteral formulations must be administrated. To avoid the adverse effects of supplements it is important to explain the terms and conditions and overall knowledge of side effects to patient. For iron supplements, patient should be cautioned for not to chew or crush the supplement.

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