Quiz 15: Psychotomimetic Drugs of Abuse

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Psychotomimetic drugs are those which can produce psychic effects in the individual. It leads to behavioral changes in the individual. These drugs have no therapeutic effect and uses. The syndrome is the set of symptoms or effects produced by the intake of drug. Intake of psychotomimetic drugs causes psychotomimetic syndrome in the individual which includes sensory distortions and pseudohallucinations. It leads to disruption of thoughts, depersonalization and unreal sensory feelings which are the most common psychic syndrome of these drugs. Elevated body temperature, high blood pressure, dilated pupils, tachycardia and psychosis are common symptoms shown by intoxication of psychotomimetic drugs.

Psychoactive drugs are those which can produce psychic effects in the individual. It leads to behavioral changes in the individual. These drugs have no therapeutic effect and uses. a. LSD intoxication should be treated with benzodiazepine antianxiety agents or barbiturates. These drugs cause sedation in the patient and help to calm the patient. It is a standard therapy for treatment of LSD intoxication. These drugs help to protect the patient from accidental injury and harming itself. b. Cocaine intoxication should be treated with Diazepam. It helps to control seizures and sedate the patient. Other drugs of use are chlorpromazine and haloperidol. These drugs antagonize neurotransmitters dopamine and norepinephrine which are increased by cocaine intoxication.

The 'neurotransmitters (N.T.)' are chemical messengers that serve to transmit signal from one neuron to another neuron. The four major N.T. that regulate mood are Serotonin, Dopamine, Gamma-amino-butyric-acid (GABA) and Nor-epinephrine. The N.Ts can be either excitatory or inhibitory in nature. The examples of excitatory N.T.s are acetylcholine and nor-epinephrine while examples of inhibitory N.T.s are dopamine, serotonin and GABA. The excitatory N.T. acetylcholine is found to be present at the neuromuscular junction (NMJ). Hence the incorrect options are a, b, d and e. The serotonin is the neurotransmitter whose interaction explains the mechanism of action of lysergic drug (LSD) and other hallucinogens. It is an example of inhibitory neurotransmitter (NT). Hence the correct option is img .

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