Quiz 12: Chromosomes and Human Inheritance

Biology

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The length and shape, centromere location of chromosomes in a cell are compared to construct karyotypes. Karyotyping is a diagnostic test in which the metaphase chromosomes of an individual are arranged into groups basing on the length, shape, and centromere location. This is because there is a wide variation in the chromosome lengths, shapes and centromere position. The position of the centromere differs for each chromosome, which can be clearly visualized and prove a better characteristic for classification of chromosomes into metacentric, sub-metacentric, and acrocentric chromosomes. Basing on this, many disorders can be identified by comparing it to the standard karyotyping chart.

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