Quiz 4: Thanks, Dad, the Economist


The Oliver Rando of the University of Massachusetts as well as his colleagues had observed to another metabolically organ that is considered to be a crucial one such as liver. In order to mimic the starvation, they fed a group of male mice with the diet that contains the 11% of protein that is very low levels of proteins for the rodents. Another group of male mice are fed with the normal diet that contains the protein of 20% for about 9 to 12 weeks of diet; the males were given the chance to access to females who were on the normal diet for mating. Later the males were separated from their females in order to reduce the effect on their progeny. After the birth, those progeny were considered to be reared by mothers until three weeks where in the level, they were killed to inspect their livers and study the genes activity related to metabolism. The Dr. Rando and his team had discovered the 445 genes whose expression is considered to be observed to depend highly on the diet of the father compared mother. Particularly, the genes that are considered to relate with the fat as well as the cholesterol synthesis were significantly more active in the offspring of the fathers fed with low protein compared to normal diet males.

The father-to-be are being advised to go for the diet with low protein compared to normal or high protein diet. The genes related to the fat as well as the cholesterol synthesis were considered to be highly active in the offspring of the fathers. The father-to-be are mostly considered to be given more of preference to the diet as the offspring carries the fat and also the cholesterol synthesis. The metabolism process depends on the diet of their fathers due to the genomic information transferred from the fathers. The fathers have more effect on the offspring compared to mothers.

The observations are made in the olden days where the famines were prevalent, the experiments made on the rodents are considered to suggest the accidental results to the evolutionary changes and in the case of food scarcity. The offspring of the mothers experiencing starvation resulted hard times in their lives of future as their adjusting to the calories intake that is of hoard. Thus, such adaptation would result in the weight put on with unpleasant situations and would lead to the response to the fetus from the mother through the placenta. In some of the cases the unfertilized ovum is considered to have effect. It is considered to have the bad effect on the offspring related genes and thereby to the coming generations. This can be seen in the case of sperm of the putative fathers where they meant to be starved during the time of mating.

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