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Concepts of Genetics 11th Edition by William Klug,Michael Cummings,Charlotte Spencer,Michael Palladino
Edition 11ISBN: 9781292139456Concepts of Genetics 11th Edition by William Klug,Michael Cummings,Charlotte Spencer,Michael Palladino
Edition 11ISBN: 9781292139456 Exercise 17
There are at least eight known progressive neuronal dysfunction diseases in humans that are caused by abnormal numbers of CAG repeats within the coding regions of specific genes. Genes carrying such mutations are typically of the gain-of-function class and often share a common mechanism of progressive pathogenesis. Why are such genes "gain-of-function"? Speculate on why such diseases are probably caused by a common mechanism of pathogenesis.
Explanation
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Genes which contain multiple CAG repeats...
Concepts of Genetics 11th Edition by William Klug,Michael Cummings,Charlotte Spencer,Michael Palladino
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