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Concepts of Genetics 11th Edition by William Klug,Michael Cummings,Charlotte Spencer,Michael Palladino
Edition 11ISBN: 9781292139456Concepts of Genetics 11th Edition by William Klug,Michael Cummings,Charlotte Spencer,Michael Palladino
Edition 11ISBN: 9781292139456 Exercise 16
Fragile-X syndrome is characterized by intellectual deficits, some dysmorphia, and hyperactivity. It is caused by abnormal expansion of a (CGG) n repeat in the 5'-untranslated region of the FMR1 gene and as such results in hypermethylation of CpGs. Considering the role of the FMR1 gene in expression of fragile-X syndrome, what is the relationship between hypermethylation and FMR1 gene expression?
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DNA hypermethylation will lead to the do...
Concepts of Genetics 11th Edition by William Klug,Michael Cummings,Charlotte Spencer,Michael Palladino
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