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Concepts of Genetics 11th Edition by William Klug,Michael Cummings,Charlotte Spencer,Michael Palladino
Edition 11ISBN: 9781292139456Concepts of Genetics 11th Edition by William Klug,Michael Cummings,Charlotte Spencer,Michael Palladino
Edition 11ISBN: 9781292139456 Exercise 19
The apterous gene in Drosophila encodes a protein required for wing patterning and growth. It is also known to function in nerve development, fertility, and viability. When human and mouse genes whose protein products closely resemble apterous were used to generate transgenic Drosophila (Rincon-Limas et al. 1999. Proc. Nat. Acad. Sci. [ USA ] 96: 2165-2170), the apterous mutant phenotype was rescued. In addition, the whole-body expression patterns in the transgenic Drosophila were similar to normal apterous.
(a) What is meant by the term rescued in this context?
(b) What do these results indicate about the molecular nature of development?
(a) What is meant by the term rescued in this context?
(b) What do these results indicate about the molecular nature of development?
Explanation
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▪rescued phenotype means that the pheno...
Concepts of Genetics 11th Edition by William Klug,Michael Cummings,Charlotte Spencer,Michael Palladino
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