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Concepts of Genetics 11th Edition by William Klug,Michael Cummings,Charlotte Spencer,Michael Palladino
Edition 11ISBN: 9781292139456Concepts of Genetics 11th Edition by William Klug,Michael Cummings,Charlotte Spencer,Michael Palladino
Edition 11ISBN: 9781292139456 Exercise 26
Incorrectly spliced RNAs often lead to human pathologies. Scientists have examined human cancer cells for splice-specific changes and found that many of the changes disrupt tumor-suppressor gene function (Xu and Lee, 2003. Nucl. Acids Res. 31: 5635-5643). In general, what would be the effects of splicing changes on these RNAs and the function of tumor-suppressor gene function? How might loss of splicing specificity be associated with cancer?
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Tumor-suppressor genes regulate cellular...
Concepts of Genetics 11th Edition by William Klug,Michael Cummings,Charlotte Spencer,Michael Palladino
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