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Concepts of Genetics 11th Edition by William Klug,Michael Cummings,Charlotte Spencer,Michael Palladino
Edition 11ISBN: 9781292139456Concepts of Genetics 11th Edition by William Klug,Michael Cummings,Charlotte Spencer,Michael Palladino
Edition 11ISBN: 9781292139456 Exercise 26
Tandemly repeated DNA sequences with a repeat sequence of one to six base pairs-for example, (GACA) n -are called microsatellites and are common in eukaryotes. A particular subset of such sequences, the trinucleotide repeat, is of great interest because of the role such repeats play in human neurodegenerative disorders (Huntington disease, myotonic dystrophy, spinal-bulbar muscular atrophy, spinocerebellar ataxia, and fragile-X syndrome). Following are data (modified from Toth et al., 2000) regarding the location of microsatellites within and between genes. What general conclusions can be drawn from these data?
Percentage of Microsatellite DNA Sequences within Genes and between Genes
Percentage of Microsatellite DNA Sequences within Genes and between Genes
Explanation
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From the data it looks as if the microsa...
Concepts of Genetics 11th Edition by William Klug,Michael Cummings,Charlotte Spencer,Michael Palladino
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