The genetic condition Xeroderma pigmentosum,which can lead to skin cancer,results from
A) inability to correct UV induced dimers.
B) inability to process phenylalanine.
C) inability to produce functional haemoglobin.
D) inability to correct transitions.
E) breaks in the X chromosome.

Question

Quizplus · Accepted Answer

Xeroderma pigmentosum is a genetic condition characterized by sensitivity to sunlight and a high risk of skin cancer. This condition is caused by defects in the nucleotide excision repair (NER) pathway, which recognizes and repairs UV-induced DNA damage, such as thymine dimers. Individuals with Xeroderma pigmentosum have a defective NER pathway, leading to a buildup of DNA damage and an increased risk of developing skin cancer. Therefore, the answer is A, inability to correct UV-induced dimers.

The Genetic Condition Xeroderma Pigmentosum,which Can Lead to Skin Cancer,results